Transcriptomics

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Foxc1 and Foxc2 are necessary to maintain glomerular podocytes


ABSTRACT: Foxc1 and Foxc2 are highly expressed in adult podocytes. To bypass embryonic lethality of Foxc1 and Foxc2 KO, mice ubiquitously expressing inducible-Cre (ROSA26-CreERT2) were mated with floxed-Foxc1 and floxed-Foxc2 mice. We used microarrays to detail effects of deletions of Foxc1 and Foxc2 on podocyte gene expression profiles in adult podocyte in vivo and in vitro.

ORGANISM(S): Mus musculus

PROVIDER: GSE117571 | GEO | 2018/07/25

REPOSITORIES: GEO

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