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Gene expression signatures for gata4/5/6 knocking down in zebrafish

ABSTRACT: Zebrafish gata4/5/6 are known to lie on the apex of the regulatory hierarchy in primitive myelopoiesis. However, little is known about the roles of microRNAs in this process. Performing microarray analysis on the expression changes of microRNAs in the gata4/5/6 knockdown embryos, we found that miR-210-5p is a novel regulator in zebrafish primitive myelopoiesis. To uncover the target genes of miR-210-5p to mediate its role in inhibiting zebrafish primitive myelopoiesis, we performed microarray analysis to identify differentially expressed genes in gata4/5/6 knockdown embryos.

ORGANISM(S): Danio rerio

PROVIDER: GSE117958 | GEO | 2021/07/30

REPOSITORIES: GEO

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MicroRNA expression signatures for gata4/5/6 knocking down in zebrafish

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