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Lung airways reprogram circulating memory CD8 T cells

ABSTRACT: To examine how the transcriptome of circulating memory CD8 T cells isolated from the spleen are reprogrammed in the lung airways, influenza nucleoprotein-specific CD8 T cells from the spleen were FACS sorted and RNA isolated for RNA-seq or the cells were transferred to the lung airways and allowed to rest for 2 days. Following 2 days, donor influenza nucleoprotein-specific CD8 T cells were FACS sorted and RNA isolated for RNA-seq..

ORGANISM(S): Mus musculus

PROVIDER: GSE118110 | GEO | 2020/01/09

REPOSITORIES: GEO

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