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Expression data of ex vivo purified CD4+ cells from WT and P2rx7-/- mice

ABSTRACT: Extracellular adenosine triphosphate (eATP) is a signaling molecule that affects T cell function via the ionotropic P2X7 receptor. The study of effector/memory T cells isolated from mice with deletion of P2rx7, the gene encoding for P2X7, allowed understanding the impact of P2X7 activity on T cell function in the eATP-rich tumor microenvironment. To explore the the transcriptional impact of the lack of P2rx7 in CD4+ naïve and TEM cells, we performed genome-wide expression profiling of ex vivo purified CD4+ naïve and TEM cells from WT and P2rx7-/- mice

ORGANISM(S): Mus musculus

PROVIDER: GSE118146 | GEO | 2020/07/24

REPOSITORIES: GEO

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