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Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus

ABSTRACT: We apply geographical position sequencing (Geo-seq), a method that combines laser capture microdissection (LCM) and single-cell RNA-seq technology, to investigate the heterogeneous nature of suprachiasmatic nucleus (SCN) in adult mouse. The 3D quantitative data enables spatial gene expression pattern visualization . The dataset identified genes that are coexpressed in a specific region, mark domains of similar global pattern of expression, and can be used for mapping the position of single cells dissociated from adult SCN.

ORGANISM(S): Mus musculus

PROVIDER: GSE118403 | GEO | 2019/06/19

REPOSITORIES: GEO

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Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus

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