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Targeting NSD2 in mouse prostate cancer cells

ABSTRACT: Transcriptome analysis of mouse prostate cancer cell line (NPK) silenced for Nsd2 using shRNA or treated with MCTP--39. NPK prostatre cancer cells are derived Nkx3.1CreERT2/+ ;Ptenflox/flox;KrasLSL-G12D/+ mice, and were used to silence the histone methyltransferase NSD2 or treat them with the NSD2 inhibitor MCTP39 for subsequent gene expression profiling by RNAseq

ORGANISM(S): Mus musculus

PROVIDER: GSE118784 | GEO | 2019/07/23

REPOSITORIES: GEO

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