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Genome-wide map of AR-targets in human endometrial stromal cells treated with DHT.

ABSTRACT: Polycystic ovary syndrome (PCOS) is a common gynaecological disorder, characterised by elevated circulating androgens and aberrant expression of androgen receptor (AR) in the endometrium: The objective of this study is to evaluate the targets of AR in PCOS patients. Overexpression of AR and altered endometrial signalling pathways in PCOS patients may impact on a correct decidualization response, critically affecting the events surrounding embryo implantation and causing infertility.

ORGANISM(S): Homo sapiens

PROVIDER: GSE119432 | GEO | 2019/12/31

REPOSITORIES: GEO

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