Transcriptomics

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Gene expression signatures in FAM46C (TENT5C)-deleted multiple myeloma (MM) cell lines


ABSTRACT: To investigate the effect of FAM46C disruption on gene expression, we generated FAM46C-knockout (FAM46C-KO) cell clones using CRISPR/Cas9 system with MM cell lines OCI-My5, KMS-11, and ANBL-6. Using the generated cell clones, we have employed whole genome microarray expression profiling as a discovery platform to identify genes that are associated with FAM46C expression in MM cell lines. OCI-My5, KMS-11, and ANBL-6 cell clones were cultured for 48 h in vitro.

ORGANISM(S): Homo sapiens

PROVIDER: GSE119451 | GEO | 2018/09/05

REPOSITORIES: GEO

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