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Cortical transcriptome analysis of Cyfip2 mutant mice

ABSTRACT: CYFIP2 is a component of the WAVE regulatory complex which regulates actin polymerization and branching in diverse cellular compartments. Recent molecular genetic studies identified mutations of CYFIP2 in patients with early-onset epileptic encephalopathy and microcephaly, suggesting that CYFIP2 may have some roles in embryonic brain development. To understand its functions in vivo at the molecular level, we performed RNA-seq analysis in embryonic Cyfip2 mutant mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE119570 | GEO | 2021/09/06

REPOSITORIES: GEO

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