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M6A-seq data analysis of control and PCIF1 knockdown transcriptome

ABSTRACT: Purpose: To identify the in vivo RNA targets of PCIF1, we performed meRIP experiments for PCIF1 KD and control cells using an anti-m6A antibody. We envisioned that the cap-specific PCIF1 should selectively alter the m6Am modification at the 5-terminal region of transcripts. Indeed, we observed a reduction of modification peaks at the 5’-end but not the 3’-UTR regions of mRNA upon PCIF1 KD.

ORGANISM(S): Homo sapiens

PROVIDER: GSE120229 | GEO | 2018/12/20

REPOSITORIES: GEO

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