Genomics

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MYCN knock-down leads to DNA-repair deficiency in human neuroblastoma (ChIP-Seq)


ABSTRACT: We knock down MYCN in human neuroblastoma cell line by RNAi. MYCN knock-down caused global epigenome change, including nucleosome gain on key DNA-repair genes and promoter H3K9ac down regulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE120856 | GEO | 2019/06/30

REPOSITORIES: GEO

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