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LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [ChIP-Seq]

ABSTRACT: We characterized the changes in histone modifications as well as the localization of LSD1 and GFI1B for both wt SET-2 and drug-resistant SET-2 LSD1 (Leu659_Asn660insArg) treated with GSK-LSD1

ORGANISM(S): Homo sapiens

PROVIDER: GSE121424 | GEO | 2019/01/23

REPOSITORIES: GEO

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LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq]

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Human small intestinal organoids grown with a specific protocol to enrich for Paneth cells were treated with an inhbitor (GSK-LSD1) for the epigenetic modulator LSD1.

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