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RNA stability profiling in SETD2 and METTL14 knockdown HepG2 cells

ABSTRACT: To evaluate the effect of SETD2 and METTL14 on mRNA stability, we conducted RNA-seq in SETD2 or METTL14 knockdown HepG2 cells as well as control cells with or without actinomycin D treatment. Our RNA stability profiling revealed that depletion of SETD2 and METTL14 resulted in global reduction of RNA stability, and the changes were correlated between SETD2 and METTL14 knockdown cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE121949 | GEO | 2019/02/21

REPOSITORIES: GEO

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