RNAseq on induced endoreplicating S2 cells
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ABSTRACT: RNA-Seq was used In order to evaluate the global transcriptomic changes of CycA dsRNA and Myb dsRNA induced endoreplicating cells (iECs) in DrosophilaS2-DGRC cells. CycA dsRNA and Myb dsRNA iECs mRNA levels were compared to control mitotic cycling cells treated in parallel with GFP dsRNA, in three biological replicates. The RNA-Seq results indicated that a switch from mitotic cycles to endoreplication is associated with up and down regulation of thousands of genes. Comparison of the CycA dsRNA and Myb dsRNA iEC transcriptomes revealed that they shared a total of 966 genes that were differentially expressed compared to mitotic cycling controls
ORGANISM(S): Drosophila melanogaster
PROVIDER: GSE121955 | GEO | 2019/06/22
REPOSITORIES: GEO
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