RNA-seq of HUVEC ± shRNA knockdown of SENCR

ABSTRACT: To assess the transcriptome of HUVEC where the SENCR is knocked down. SENCR is a lncRNA we show stabilizes the endothelial cell adherens junction by binding CKAP4 and indirectly localizing CDH5 at the cell membrane. The RNA-seq study was carried out to ascertain whether the effects of SENCR could be attributed to a function associated with sponging endogenous microRNAs that target proteins of the adgherens junction.

ORGANISM(S): Homo sapiens

PROVIDER: GSE122490 | GEO | 2018/12/07

REPOSITORIES: GEO