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A Predictive Response Signature to Infliximab Treatment in Ulcerative Colitis

ABSTRACT: Infliximab, an anti-TNFa monoclonal antibody, is an effective treatment for ulcerative colitis (UC) inducing over 60% of patients to respond to treatment. Consequently, about 40% of patients do not respond. This study analyzed mucosal gene expression from patients enrolled in ACT1 to provide a predictive response signature for infliximab treatment. Keywords: predictive response signature

ORGANISM(S): Homo sapiens

PROVIDER: GSE12251 | GEO | 2009/08/25

SECONDARY ACCESSION(S): PRJNA113623

REPOSITORIES: GEO

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Transcription profiling of human ulcerative colitis samples reveals a predictive response signature to infliximab treatment in ulcerative colitis

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2009-09-05 | E-GEOD-12251 | biostudies-arrayexpress

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