Transcriptomics

Dataset Information

0

Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1]


ABSTRACT: The purpose of this study was to define unique classes of EWS/FLI target genes and the distinct set of structural features present in the EWS domain required for target gene regulation at different EWS/FLI response elements. This study reports the first genome-wide transcriptomic description of a partially-functional EWS/FLI mutant . We report new structure-function dependencies across different classes of response element and tie these dependencies to the ability of EWS/FLI to transform cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE122535 | GEO | 2019/02/21

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-02-21 | GSE122536 | GEO
2019-02-21 | GSE122537 | GEO
| PRJNA505499 | ENA
| PRJNA505501 | ENA
| PRJNA505502 | ENA
2021-07-06 | PXD016052 | Pride
2020-05-12 | GSE144651 | GEO
2017-10-22 | GSE94502 | GEO
2017-10-22 | GSE94480 | GEO
2020-05-12 | GSE132709 | GEO