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MEF FAN TNF

ABSTRACT: FAN (Factor associated with neutral sphingomyelinase activation) is an adaptor protein that constitutively binds to TNF-R1. Microarray analysis was performed in fibroblasts derived from wild-type or FAN knockout mouse embryos to evaluate the role of FAN in TNF-induced gene expression. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Keywords: genetic modification

ORGANISM(S): Mus musculus

PROVIDER: GSE12275 | GEO | 2009/08/31

SECONDARY ACCESSION(S): PRJNA113661

REPOSITORIES: GEO

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