Transcriptomics

Dataset Information

0

Expression data from freshly isolated mouse mammary luminal cells


ABSTRACT: The mammary luminal cell compartment is heterogeneous. In adult virgin mice, it contains clonogenic luminal progenitors and non-clonogenic luminal cells expressing estrogen and progesterone receptors that can be discrimated by their cell surface expression of ICAM-1. We have separated ICAM1+ luminal progenitors and ICAM- non-clonogenic luminal cells and analyzed their transcriptomic profiles. After showing that the luminal progenitor population overexpressed Met, Trp53 and numerous p53 target genes, we analyzed how the p53 and Met signaling pathways cooperate to control the function and plasticity of luminal progenitors.

ORGANISM(S): Mus musculus

PROVIDER: GSE122928 | GEO | 2019/02/05

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2014-11-26 | GSE47376 | GEO
2014-11-26 | E-GEOD-47376 | biostudies-arrayexpress
2024-10-16 | GSE270761 | GEO
2013-07-26 | GSE37223 | GEO
2013-07-26 | E-GEOD-37223 | biostudies-arrayexpress
2017-11-10 | E-MTAB-6160 | biostudies-arrayexpress
2016-12-20 | GSE77497 | GEO
2021-02-02 | E-MTAB-10054 | biostudies-arrayexpress
2016-12-20 | GSE77496 | GEO
2014-12-24 | E-GEOD-64487 | biostudies-arrayexpress