Genomics

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ChIP-seq analysis of transcription factor AtrR binding across the Aspergillus fumigatus genome


ABSTRACT: To determine the genomic binding sites for the Aspergillus fumigatus transcription factor AtrR, we utilized three different strains. One was the wild-type AfS35 which contains a wild-type copy of atrR but lacks any HA tag. The other two are both derived from AfS35 but contain a 3X HA tag replacing the stop codon of atrR. These strains are SPF89 and SPF112, respectively. SPF89 uses the wild-type atrR promoter to drive expression of the epitope-tagged allele while SPF112 uses the much strong hspA promoter to drive production of the same protein.

ORGANISM(S): Aspergillus fumigatus Af293

PROVIDER: GSE123159 | GEO | 2019/02/11

REPOSITORIES: GEO

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