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MiRNA expression profiles and molecular networks in resting and LPS-activated BV-2 microglia - Effect of cannabinoids

ABSTRACT: Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and cannabidiol (CBD) the non-psychoactive component, modulate the inflammatory response through miRNA expression

ORGANISM(S): Mus musculus

PROVIDER: GSE123262 | GEO | 2019/01/10

REPOSITORIES: GEO

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