Transcriptomics

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Expression data from adult mouse brain astrocytes


ABSTRACT: We aimed to investigate whether reduction of mitochondrial reactive oxygen species (mROS) in adult astrocytes altered the transcriptional profile in vivo. To do so, we used a genetic approach expressing a version of the catalase enzyme within the mitochondria of astrocytes. Astrocytes were acutely isolated from the brains of adult GFAP-mCAT and control mice by the immunomagnetic approach and subjected to a whole-genome transcriptomics array analysis. We used microarrays to detail the whole genome changes modulated by mROS levels in astrocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE124130 | GEO | 2019/02/04

REPOSITORIES: GEO

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