Expression data from Malpighian tubules of wild type and dVHL +/- Drosophila 5-days old female
Ontology highlight
ABSTRACT: Mutations in VHL tumor suppressor gene are the cause of the familial VHL disease that displays multiple benign and malignant tumors such as clear cell renal cell carcinoma. The VHL gene is similar in Drosophila melanogaster (dVHL) and humans. We used microarrays to compare the gene expression profile between yellow white (used as control) and heterozygous dVHL +/- Malpighian tubes dissected from adult Drosophila female with the aim to identify distinct classes of up-regulated and downregulated genes in a sensitized (haploinsufficient) genetic background.
ORGANISM(S): Drosophila melanogaster
PROVIDER: GSE124152 | GEO | 2019/05/28
REPOSITORIES: GEO
ACCESS DATA