Transcriptomics

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Histone demethylase KDM4A-mediated promotion of PAF1/NFATC2 expression is required for oncogenesis in MLL-AF9 acute myeloid leukemia [RNA-seq]


ABSTRACT: In this study we identified the histone demethylase KDM4A as an essential and selective regulator of AML oncogenic potential. RNAseq was used to follow the changes in gene expression following KDM4A knockdown in MLL-AF9 human AML THP-1 cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE125374 | GEO | 2021/01/17

REPOSITORIES: GEO

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