Transcriptomics

Dataset Information

0

Gene expression data from THP-1 cells exposed to exosomes from acetaminophen-treated or vehicle-treated hepatocytes or corresponding mock- or medium-controls


ABSTRACT: In the present study we examined the effect of hepatocyte-derived exosomes (HDE) on innate immune cells by treating a human monocyte cell line (THP-1 cells) with exosomes collected from the culture medium of acetaminophen (APAP)-treated and untreated primary human hepatocytes and comparing the cytokine response to THP-1 cells treated with mock- and medium-controls. We profiled the gene expression changes observed in the HDE-exposed monocytes prior to LPS stimulation. Findings from our research suggest that HDE may be essential for maintaining immune homeostasis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE125690 | GEO | 2019/12/31

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA517174 | ENA
2019-12-02 | GSE77554 | GEO
2008-06-14 | E-GEOD-5652 | biostudies-arrayexpress
2014-12-16 | E-GEOD-51969 | biostudies-arrayexpress
2013-06-08 | GSE37874 | GEO
2014-12-16 | GSE51969 | GEO
2021-10-04 | GSE183119 | GEO
2010-07-06 | E-GEOD-18614 | biostudies-arrayexpress
2013-06-08 | E-GEOD-37874 | biostudies-arrayexpress
2020-10-04 | GSE104601 | GEO