Genomics

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Investigating the role of SMCHD1 in regulating clustered protocadherin (Pcdh) and Hox genes


ABSTRACT: To investigate the effect of Smchd1 ablation on clustered Pcdh and Hox genes, we generated ChIP-seq profiles of EZH2 in clonal neural progenitor cells (NPCs) from Smchd1+/+ (wild-type, WT) and Smchd1-/- mouse embryonic stem (ES) cells. We also reanalyzed previously published Hi-C data (GSE99991) (Wang et al., 2018, Cell) in these two cell lines.

ORGANISM(S): Mus musculus

PROVIDER: GSE126257 | GEO | 2019/07/27

REPOSITORIES: GEO

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