Transcriptomics

Dataset Information

0

FAMIN is a multifunctional purine enzyme enabling the purine nucleotide cycle (Macrophage RNA Seq dataset)


ABSTRACT: FAMIN (LACC1, C13orf31) loss-of-function causes systemic juvenile idiopathic arthritis and very early-onset inflammatory bowel disease, while a common I254V substitution results in hypomorphic function and increases susceptibility to Crohn’s disease and leprosy. In this study, we compare the mRNA transcriptional profiles of M0, M1 and M2-polarised bone marrow-derived macrophages from mice engineered at their endogenous locus to express human non-risk (Faminp.254I), risk (Faminp.254V) and monogenic (Faminp.284R) disease variants.

ORGANISM(S): Mus musculus

PROVIDER: GSE126641 | GEO | 2020/01/28

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-01-04 | GSE126473 | GEO
| S-EPMC6978800 | biostudies-literature
2020-09-28 | PXD017320 | Pride
| PRJNA522787 | ENA
2018-09-30 | GSE119367 | GEO
2015-01-01 | E-GEOD-53321 | biostudies-arrayexpress
2018-04-03 | GSE112611 | GEO
2023-01-14 | E-MTAB-12498 | biostudies-arrayexpress
| PRJNA789868 | ENA
2024-09-30 | GSE272811 | GEO