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MiRNA sequencing of synovial fluid derived extracellular vesicles between normal and osteoarthritis (OA) patients

ABSTRACT: To determine whether extracellular vesicles were also present in human disease, we isolated and evaluated extracellular vesicles from synovial fluid from normal and OA patients at relatively advanced ages (70 - 80 years). Here we report the altered expression of synovial fluid extracellular vesicles-derived miRNAs in osteoarthritis compared to normal patients with age-relate degeneration to investigate potential biomarkers for OA diagnosis. The OA donors had clinical evidence of OA based on pain that led to total joint arthroplasty.

ORGANISM(S): Homo sapiens

PROVIDER: GSE126677 | GEO | 2019/02/18

REPOSITORIES: GEO

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miRNA sequencing of synovial fluid derived extracellular vesicles between normal and osteoarthritis (OA) patients

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