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Genomic profiling of MondoA and H3K27ac in primary human skeletal myotubes

ABSTRACT: It is well known that insulin resistance in the obese state is associated with accumulation of neutral lipid in extra-adipose tissues. This phenomenon is particularly well-documented in skeletal muscle. The mechanistic underpinnings of this linkage are not fully understood. To define direct MondoA target genes, we performed MondoA ChiP sequencing in human myotubes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE126733 | GEO | 2019/08/22

REPOSITORIES: GEO

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Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown

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