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The Wnt pathway inhibitor, LGK974 has suppressive effects for LPS-induced endotoxemia

ABSTRACT: We demonstrated that Wnt/β-catenin pathway was activated in in endotoxemic mice, and the modulation of this pathway by LGK974 had beneficial effects by suppressing the inflammation and lethality caused by endotoxemia.

ORGANISM(S): Mus musculus

PROVIDER: GSE127459 | GEO | 2019/03/01

REPOSITORIES: GEO

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The Wnt pathway inhibitor, LGK974 has suppressive effects for LPS-induced endotoxemia

Project description:The Wnt pathway inhibitor, LGK974 has suppressive effects for LPS-induced endotoxemia

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