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Renal Proximal Tube Epithelial Cells at 24h and 1% oxygen

ABSTRACT: Aim of the study was to characterize the transcriptional response of human primary renal proximal tubule epithelial cells (RPTEC) to low oxygen stress.

ORGANISM(S): Homo sapiens

PROVIDER: GSE12792 | GEO | 2008/09/17

SECONDARY ACCESSION(S): PRJNA112789

REPOSITORIES: GEO

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Transcription profiling of human renal proximal tube endothelial cells at 24h and 1%oxygen

Project description:Aim of the study was to characterize the transcriptional response of human primary renal proximal tubule endothelial cells (RPTEC) to low oxygen stress. Experiment Overall Design: Passage 4 renal proximal tubule epithelial cells were exposed to a humidified atmosphere consisting of either 5% CO2 and 95% air (20% O2, normoxia) or 5% CO2, 1% oxygen and 95% nitrogen (hypoxia) for 24 hours. Total RNA was extracted immediately after exposure. Three independent biological replicates were performed, resulting in 6 samples (3 control and 3 low oxygen).

2008-10-25 | E-GEOD-12792 | biostudies-arrayexpress

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