Transcriptomics

Dataset Information

0

Next Generation Sequencing Facilitates Quantitative Analysis of SCs in mice exposure to exercise


ABSTRACT: Purpose:To identify genes and the molecular pathways involved in the regulation of muscle satellite cells (SCs) in mice exposure to running exercise, we performed RNA-Sequence of SCs in untrained (Con) and trained mice (Exe). Methods: mRNA profiles of SCs in untrained (Con) and trained mice (Exe) (running exercise, 4 days/week, 30 min/day at 12 m/min) were generated by deep sequencing, in quadruplicate, using Illumina HiSeq 2000. Results:Using an optimized data analysis workflow, we mapped about 9 million sequence reads per sample to the mouse genome (build mm10) and identified 9031 transcripts in SCs (the control and exercise group) with BWA workflow. Conclusions: Our results represent the first detailed analysis of SCs transcriptomes in mice exposure to running exercise and found that exercise regulated multiple mRNA pathways in SCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE128651 | GEO | 2020/06/08

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2011-12-15 | E-GEOD-28998 | biostudies-arrayexpress
2019-02-16 | GSE120862 | GEO
2022-12-01 | GSE198652 | GEO
2022-02-24 | PXD003982 | Pride
2016-04-05 | E-GEOD-79894 | biostudies-arrayexpress
2009-11-16 | GSE13623 | GEO
2009-11-15 | E-GEOD-13623 | biostudies-arrayexpress
2023-08-04 | GSE221210 | GEO
2023-08-04 | GSE221831 | GEO
2008-06-13 | E-GEOD-5297 | biostudies-arrayexpress