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RNA-seq analysis of dolastatin 15 treatment in HCT116 cells

ABSTRACT: Dolastatin 15 is a known tubulin binding agent and shows remarkable differential cytotoxicity against a panel of colorectal HCT116 isogenic cells. The compound causes anti-vascularization effect in human endothelial cells (HUVEC) in a dose dependent manner. Antiangiogenic effect was further validated in a zebrafish genetic model with activated HIF

ORGANISM(S): Homo sapiens

PROVIDER: GSE128748 | GEO | 2020/03/22

REPOSITORIES: GEO

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