Inter-myeloid cell synaptic antigen dispersal drives diversified anti-tumor T cell priming
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ABSTRACT: Using a labelled tumor antigen we identify dendritic cell subsets containing tumor derived antigen in the tumor draining lymph nodes and used these to stimulate anti-tumor OTI CD8 T cells. These were subsequently interrogated by RNAseq to determine how diverse DC subsets drive distinct patterns of CD8 T cell differentiation
ORGANISM(S): Mus musculus
PROVIDER: GSE128980 | GEO | 2020/11/27
REPOSITORIES: GEO
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