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RG4-seq for P. aeruginosa and E. coli


ABSTRACT: Escherichia coli is the most widely studied strains, which has irreplaceable position in medicine and biology research. Pseudomonas aeruginosa, an opportunistic human pathogen, tends to cause potentially lethal acute or chronic infections in patients with cystic fibrosis (CF), immunocompromised individuals and burn victims. However, it is little know about the effect of the special secondary structure rG4 (G-quadruplex) in the mRNA on virulence regulation. Here, we aim to reveal the new and important post-transcriptional regulatory roles of rG4 in bacterial pathogenicity and metabolic pathways.

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 Pseudomonas aeruginosa PAO1

PROVIDER: GSE129281 | GEO | 2019/12/31

REPOSITORIES: GEO

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