Exploring Listeria monocytogenes transcriptomes in correlation with divergence of lineages and virulence measured in Galleria mellonella

ABSTRACT: For bacteria in general and Listeria monocytogenes in particular, little is known about transcriptome diversity in comparison to the copious data on intraspecific genome diversity. The current study employed RNA sequencing to investigate the variation of transcript levels of conserved single copy genes from several perspectives including differences between lineages and correlation with previous classification of the virulence potential of clonal complexes based on epidemiological MLST data. Infection of G. mellonella, a surrogate host, also allowed a correlation analysis with virulence data experimentally determined in vivo.

ORGANISM(S): Listeria monocytogenes

PROVIDER: GSE129537 | GEO | 2019/09/10

REPOSITORIES: GEO