Transcriptomics

Dataset Information

0

RNA-seq based transcriptomic profiling of GBM44 glioma cell line with BAT1 shRNA knockdown


ABSTRACT: Purpose: We found that BAT1 plays key role in the regulation of immune related factors, we aim to characterize the genes changed after BAT1 knockdown Methods: Gene expression profile of GBM44 control and BAT1 knockdown were generated by deep sequencing, in triplicate, using Illumina HiSeq 4000 Results: Using an optimized data analysis pipeline(HISAT2/HT-Seq/DESeq2), 5209 differentially expression protein-coding and noncoding genes (cut-off adjusted P <0.01) were identified in response to BAT1 knockdown. Conclusions: After BAT1 knockdown, thousands of genes are differentially regulated, and these genes participate in immuse defense, Inflammatory response as well as cell migration and proliferation (GO pathway analysis).

ORGANISM(S): Homo sapiens

PROVIDER: GSE129542 | GEO | 2020/03/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2018-04-12 | GSE97371 | GEO
2021-08-22 | GSE182142 | GEO
2021-01-26 | GSE147352 | GEO
2021-04-30 | GSE173621 | GEO
2021-04-30 | GSE173575 | GEO
2021-06-19 | GSE178487 | GEO
2024-04-18 | GSE260692 | GEO
2021-03-24 | GSE169344 | GEO
2021-11-10 | GSE163798 | GEO
2019-10-18 | GSE139018 | GEO