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Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis

ABSTRACT: Follow-up work was performed for SF3A2, a gene among the hits identified in a red blood cell trait GWAS-informed shRNA screen. Differential splicing effects were assayed to investigate resulting effects on the differentiating erythroid cell spliceome and explore potential modifier relationships with other known splicing defects associated with human disease.

ORGANISM(S): Homo sapiens

PROVIDER: GSE129603 | GEO | 2019/04/11

REPOSITORIES: GEO

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Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.

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