Transcriptomics

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Disease modelling of core pre-mRNA splicing factor haploinsufficiency


ABSTRACT: We generated a human EFTUD2 knockdown cell line using a CRISPR cas9 nickase strategy to investigate the effects of decreased expression of core spliceosome components on cell characteristics and global transcriptome expression/splicing patterns

ORGANISM(S): Homo sapiens

PROVIDER: GSE129619 | GEO | 2019/04/12

REPOSITORIES: GEO

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