Atrx deletion in neurons leads to sexually-dimorphic dysregulation of miR-137 and spatial learning and memory deficits
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ABSTRACT: Ablation of the ATRX chromatin remodeler specifically in forebrain excitatory neurons of mice causes male-specific deficits in long-term spatial memory associated with miR-137 overexpression, transcriptional changes and structural alterations corresponding to pre- and post-synaptic abnormalities.
ORGANISM(S): Mus musculus
PROVIDER: GSE129975 | GEO | 2020/06/30
REPOSITORIES: GEO
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