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Transcript profiling of Actinobacillus pleuropneumoniae in BALF

ABSTRACT: Actinobacillus pleuropneumoniae is the etiologic agent of contagious pleuropneumonia, an economically important disease of commercially reared swine throughout the world. To cause this disease, A. pleuropneumoniae must rapidly overcome porcine pulmonary innate immune defenses. Since bronchoalveolar fluid (BALF) contains many of the innate immune components found in the lung, we examined the gene expression of a virulent serovar 1 strain of A. pleuropneumoniae after exposure to concentrated BALF. This experiment was also carried out with a malT mutant of the same strain.

ORGANISM(S): Actinobacillus pleuropneumoniae serovar 5b str. L20 Actinobacillus pleuropneumoniae

PROVIDER: GSE13006 | GEO | 2009/01/06

SECONDARY ACCESSION(S): PRJNA110933

REPOSITORIES: GEO

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