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Effects of overexpression of EhMyb-dr on transcription in Entamoeba histolytica

ABSTRACT: A myb domain containing protein of the SHAQKY family, EhMyb-dr, was overexpressed in E. histolytica trophozoites, and effects on transcription were measured.

ORGANISM(S): Entamoeba histolytica

PROVIDER: GSE13023 | GEO | 2009/03/01

SECONDARY ACCESSION(S): PRJNA112565

REPOSITORIES: GEO

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Effects of overexpression of EhMyb-dr on transcription in Entamoeba histolytica

Project description:A myb domain containing protein of the SHAQKY family, EhMyb-dr, was overexpressed in E. histolytica trophozoites, and effects on transcription were measured. Two arrays of trophozoites expressing Myc tagged EhMyb-dr were compared to two arrays performed on wild type trophozoites. The effects of transfection and drug were controlled for by including data from trophozoites expressing irrelevant plasmids, and grown in the same level of G418. All parasites were of strain HM-1:IMSS

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