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Assessing chromatin accessibility in WT and STAT4-/- ILC1s

ABSTRACT: STAT4 dynamically interacts with the genomic landscape and functions in modulating chromatin accessibility to influence gene expression. We aimed to evaluate the impact of STAT4 on chromatin accessibility of colonic lamina propria ILC1s. To address this aim, we sorted ILC1s from the colonic LP of unmanipulated C57BL/6 and STAT4-/- mice and performed the assay for transposase-accessible chromatin using sequencing (ATAC-seq).

ORGANISM(S): Mus musculus

PROVIDER: GSE132769 | GEO | 2019/06/17

REPOSITORIES: GEO

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Assessing chromatin accessibility in WT and STAT4-/- ILC1s

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