Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression analysis of cells sensitive to necrosis (L929) and cells sensitive to apoptosis (NIH3T3).

ABSTRACT: To explore gene expression profiles of cells sensitive to necrosis (such as L929 cells) and those sensitive to apoptosis (such as NIH3T3 cells), we conducted expression microarray analysis of L929 cells and NIH3T3 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE13335 | GEO | 2008/10/31

SECONDARY ACCESSION(S): PRJNA109853

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcription profiling of mouse cells sensitive to necrosis (L929) and cells sensitive to apoptosis (NIH3T3).

Project description:To explore gene expression profiles of cells sensitive to necrosis (such as L929 cells) and those sensitive to apoptosis (such as NIH3T3 cells), we conducted expression microarray analysis of L929 cells and NIH3T3 cells. Experiment Overall Design: Total RNA of 2 samples of unstimulated L929 cells or 2 samples of unstimulated NIH3T3 cells were extracted by Trizol followed by RNeasy. The quantity, purity and integrity of RNA were evaluated by UV spectrophotometry and RNA-nano Bioanalyzer. Sample processing and hybridization on Mouse Genome 430 2.0 GeneChip microarrays (Affymetrix) were performed according to manufacturerâs instructions. Genes that are differentially expressed in L929 cells relative to NIH3T3 cells were identified as having an FDR-adjusted p-value <0.05 and a fold-change >1.5.

2008-11-13 | E-GEOD-13335 | biostudies-arrayexpress

Mus musculus

Project description:Gene expression analysis of cells sensitive to necrosis (L929) and cells sensitive to apoptosis (NIH3T3).

| PRJNA109853 | ENA

L929 vs L929IRF8 following 4hr IFNbeta treatment (1000U/ml)

Project description:Identify genes like Ifit1 which are induced in L929 cells but not L929 cells expressing ectopic IRF8

2016-04-30 | GSE75126 | GEO

Comparison of mock treated L929 cells with L929 cells infected with wildtype versus nt3A mutant VRP at 5hpi

Project description:This series includes arrays from two separate experiments where the gene expression profile of mock treated L929 cells was compared to that of L929 cells that had been infected with wildtype versus nt3A mutant Venezuelan equine encephalitis virus replicon particles (VRP). Total RNA was isolated from all samples at 5 hour post-infection. Keywords: virus infection-induced gene expression changes

2007-04-28 | GSE7647 | GEO

Effect of TNF-α on gene expression of L929 cells

Project description:To investigate the TNF-α in the regulation of L929 cells.We performed gene expression profiling analysis using data obtained from RNA-seq of L929 cells activated by TNF-α.

2022-05-09 | GSE202376 | GEO

Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation

Project description:Bone marrow-derived macrophages (BMDMs) are a key model system for studying macrophage biology in vitro. Commonly used methods to differentiate macrophages from bone marrow are treatment with either recombinant M-CSF or the supernatant of L929 cells, which secrete M-CSF. However, little is known about the composition of L929 conditioned media (CM) and how it affects BMDM phenotype. Here, we used quantitative mass spectrometry to characterise the kinetics of protein secretion from L929 cells over a two-week period. While M-CSF is very abundant in L929 CM, we identified several other immune-regulatory proteins at surprisingly high abundance. L929 CM induced a slightly pre-activated phenotype and the expression of a number of known innate immune proteins in macrophages. This resource will be valuable to all researchers using L929 CM for the differentiation of BMDMs.

2021-04-13 | PXD021026 | Pride

Nutrient-dependent growth of NIH3T3 and NIH3T3 K-ras cell lines.

Project description:Expression profiling of normal NIH3T3 and transformed NIH3T3 K-ras cell lines grown for 72 hours in optimal glucose availability (25 mM glucose) or low glucose availability (1 mM). Low glucose induces apoptosis in transformed cells as compared to normal ones.

2011-07-14 | GSE29962 | GEO

Murine NIH3T3 Cells: Wild vs. BRAFV600E Transfected

Project description:Transcriptional profiling of mouse NIH3T3 cells comparing control NIH3T3 cells transfected with a pEFm6-BRAF with cells transfected with pEFm6-BRAFV600E. Goal was to determine the effects of BRAFV600E gene transfection on global mouse NIH3T3 cells gene expression.

2017-01-01 | GSE90589 | GEO

Apatite nanoparticle(sCA)-siTIMP1 delivery in NIH3T3

Project description:Expression profiling of sCA-siRNA delivery in NIH3T3 cells (siControl vs. siTIMP1) Goal was to determine the off target effects of sCA-siTIMP1 in NIH3T3 cells.

2020-08-27 | GSE128124 | GEO

Gene expression after type-I interferon treatment in primary neurons, primary fibroblasts and L929 cells

Project description:Microarray expression profilling of mouse primary mixed cortical/hippocampal neurons, primary fibroblasts and L929 cells to compare ISGs signature in disctinct cell types

2014-01-10 | GSE53951 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data