ChEC-Seq: a robust method to identify protein-DNA interactions genome-wide
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ABSTRACT: Here we show that the ChEC-Seq technique is able to differentiate the binding specificities of Esa1 and Gcn5 two chromatin-binding factors displaying widespread genome-wide associations. We also show that the ChEC-Seq technique reveals strong binding of the transcription factor Sfp1 at Ribi gene promoters. Furthermore, our data provide the first evidence that a specific DNA motif previously identified by ChEC-Seq (Albert 2019 PMID: 30804227) is in fact an in vivo binding site for Sfp1.
ORGANISM(S): Saccharomyces cerevisiae
PROVIDER: GSE133645 | GEO | 2020/07/01
REPOSITORIES: GEO
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