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Next Generation Sequencing Facilitates Quantitative Analysis of the control and H2O2-treated IMR90 cells Transcriptomes

ABSTRACT: We generated 6 Gb of high-quality sequencing data (per sample) and catalogued the expression profiles of annotated genes in each sample. The analysis showed differences of transcriptomes between the control and H2O2 treatment as well as revealed that H2O2 treatment induced genes expression changes. We identified numerous differentially expressed genes that known or potential roles in cellular senescence.Therefore, they are appealing candidates for further investigation of the gene expression and associated regulatory mechanisms related to cellular senescence

ORGANISM(S): Homo sapiens

PROVIDER: GSE134088 | GEO | 2020/01/01

REPOSITORIES: GEO

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