Mapping Gata2 enhancer-dependent developmental trajectories by single-cell RNA-sequencing
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ABSTRACT: We compared single-cell transcriptomes of fetal liver myeloid progenitor pools (CMP/GMP pool) from Gata2 -77 enhancer mutant embryos and wildtype littermates. Gene expression patterns in -77-deficient mice demonstrated loss of erythroid, megakaryocyte and granulocyte progenitors and an increase in monocyte
ORGANISM(S): Mus musculus
PROVIDER: GSE134439 | GEO | 2020/06/03
REPOSITORIES: GEO
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