Transcriptomics

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Expression array of DNMT1 inhibitor treated 3 AML cell lines

ABSTRACT: Genome wide demethylation by DNMT1 inhibitor GSK3484862 results in up-regulation of epigenetically-silenced genes Differential expression was perfomed for each cell line following DNMT1 inhibitor or vehicle treatment. Differentially epressed gene lists were submitted to gene set enrichment analysis (GSEA) to identify consistently changed pathways.

ORGANISM(S): Homo sapiens

PROVIDER: GSE134742 | GEO | 2022/12/31

REPOSITORIES: GEO

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