Transcriptomics

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Dynamic analysis of m6A methylation spectroscopy during progression and reversal of hepatic fibrosis


ABSTRACT: We constructed a model of progression and reversal of hepatic fibrosis by intraperitoneal injection of carbon tetrachloride (CCl4). Dynamic m6A methylation was evaluated using MeRIP-Seq technique in the progression and reversal of hepatic fibrosis, and of the normal age-matched control groups. Genes with differentially m6A methylated sites and expression were analyzed to reveal the over-represented gene ontologies and pathways at different stages

ORGANISM(S): Mus musculus

PROVIDER: GSE135462 | GEO | 2022/07/01

REPOSITORIES: GEO

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