Transcriptomics

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RNASeq of bone lining niche cell components from healthy vs. myeloma-bearing mice


ABSTRACT: We compare gene expression in FACS-sorted bone-lining cell components: stromal progenitors, osteoprogenitors and endothelial cells, from myeloma-bearing vs. from healthy mice, and also between myeloma cells flushed from the central bone marrow vs. myeloma cells digested from the bone surface (myeloma-bearing mice only). The myeloma model used is the 5TGM1 murine myeloma cell line, injected into immunocompetent KaLwRij mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE135691 | GEO | 2019/08/14

REPOSITORIES: GEO

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